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  1. Pitanje broj: #104140

    Postovani imamlihen ruber planus. Koje infektivne bolesti i maju ovaj osip. Od vase strane sta treba da istivam. Molim vas strucni odgovor. Hvala. Pozdrav

    Odgovoreno: 26. 01. 2019.
    • LIchen planus is a recurrent, pruritic, inflammatory eruption characterized by small, discrete, polygonal, flat-topped, violaceous papules that may coalesce into rough scaly plaques, often accompanied by oral and/or genital lesions. Diagnosis is usually clinical and supported by skin biopsy. Treatment generally requires topical or intralesional corticosteroids. Severe cases may require phototherapy or systemic corticosteroids, retinoids, or immunosuppressants.

      Etiology

      Lichen planus (LP) is thought to be caused by a T cell–mediated autoimmune reaction against basal epithelial keratinocytes in people with genetic predisposition. Drugs (especially beta-blockers, NSAIDs, ACE inhibitors, sulfonylureas, gold, antimalarial drugs, penicillamine, and thiazides) can cause LP; drug-induced LP (sometimes called lichenoid drug eruption) may be indistinguishable from nondrug-induced LP or may have a pattern that is more eczematous.

      Associations with hepatitis (hepatitis B infection, hepatitis B vaccine, and, particularly, hepatitis C–induced liver insufficiency) and primary biliary cirrhosis have been reported.

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